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Millán Zambrano, GonzaloPerfil en ORCID: 0000-0002-4530-6359 Perfil en Scopus: 37023469300\ Grupos de Investigación Responsable de los siguientes proyectos/ayudas en la USParticipa los siguientes proyectos/ayudas en la USProyectos: - Latencia de la Infección por VIH-1: Mecanismos Moleculares y Estrategias de Terapia Génica Mediante Nanopartículas Dirigidas ( P12-BIO-1938 - Investigador/a).
- Regulación Cruzada Entre la Transcripción y la Estabilidad de los Mrnas: Influencia de la Cromatina y del Backtracking de la RNA Pol II ( BFU2013-48643-C3-1-P - Investigador/a).
- Determinantes genómicos del estado latente del VIH-1 y estrategias terapéuticas ( 360946/10 - Participante).
- REGULACIÓN TRANSCRIPCIONAL DE LOS GENES IMPLICADOS EN LA SÍNTESIS DE RIBOSOMAS: RELACIÓN CON LA SENSIBILIDAD A DROGAS INMUNOSUPRESORAS E INFLUENCIA DE ( P07-CVI-02623 - Investigador/a).
PublicacionesCapítulo de Libros: - Millán-Zambrano, Gonzalo:
A Matter of Packaging: In¿ uence of Nucleosome Positioning on Heterologous Gene Expression . Pag. 51 - 64. En: Methods in Molecular Biology. Recombinant Gene Expression: Reviews and Protocols, Third Edition, . Springer Science. 2012. ISBN 978-1-61779-432-2 - Muñoz-Centeno, Maria De La Cruz, Millán-Zambrano, Gonzalo, Chavez-De Diego, Sebastian:
A Matter of Packaging: Influence of Nucleosome Positioning on Heterologous Gene Expression . Pag. 51 - 64. En: Methods in Molecular Biology: Recombinant Gene Expression . . 2012. ISBN 978-1-61779-432-2
Publicaciones en Revistas: - Gutierrez-Pozo, Gabriel, Millán-Zambrano, Gonzalo, Medina, Daniel, Jordán-pla, Antonio, Pérez, José Enrique, Peñate-Salas, Xenia, Chavez-De Diego, Sebastian:
Substracting the Sequence Bias from Partially Digested MNase-seq Data Reveals a General Contribution of TFIIS to Nucleosome Dynamics. En: Epigenetics & Chromatin. 2017. Vol. 10. Núm. 1. Pag. 1-22 - Gómez-Herreros, Fernando, Cruz-Diaz, Jesus De La, Holstage, Frank, Chavez-De Diego, Sebastian, Margaritis, Thanasis, Rodríguez-galán, Olga, Pelechano, Vicent, Begley, Victoria Sarah, Millán-Zambrano, Gonzalo, Morillo-Huesca, Macarena, Muñoz-Centeno, Maria De La Cruz, Pérez-ortín, Jose E.:
The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation. En: Nucleic Acids Research. 2017. Vol. 45. Núm. . Pag. 9302-9318 - Nadal-ribelles, Mariona, Mas, Gloria, Millán-Zambrano, Gonzalo, Solé, Carme, Ammerer, Gustav, Chavez-De Diego, Sebastian, Posas, Francesc, De Nadal, Eulalia:
H3K4 monomethylation dictates nucleosome dynamics and chromatin remodeling at stress-responsive genes. En: Nucleic Acids Research. 2015. Vol. 43. Núm. 10. Pag. 4937-4949 doi: 10.1093/nar/gkv220 - Millán-Zambrano, Gonzalo, Chavez-De Diego, Sebastian:
Nuclear functions of prefoldin. En: Open Biology. 2014. Vol. 4. Núm. 7. Pag. 140185-1-140185-10 doi: 10.1098/rsob.140085 - Medina, Daniel, Jordán-pla, A, Millán-Zambrano, Gonzalo, Chavez-De Diego, Sebastian, Choder, M, Pérez-ortín, Jose Enrique:
Cytoplasmic 5'-3' exonuclease Xrn1p is also a genome-wide transcription factor in yeast. En: Frontiers in Genetics. 2014. Vol. 5. Núm. 1. Pag. 1-10 10.3389/fgene.2014.00001 - Haimovich, G, Choder, M, Medina, Da, Causs, Sz, Garber, M, Millán-Zambrano, Gonzalo, Barkai, O, Chavez-De Diego, Sebastian, Pérez-ortín, Je, Darzacq, X:
Gene expression is circular: factors for mRNA degradation also foster mRNA synthesis. En: Cell. 2013. Vol. 153. Núm. 5. Pag. 1000-1011 http://dx.doi.org/10.1016/j.cell.2013.05.012 - Millán-Zambrano, Gonzalo, Rodríguez-Gil, Alfonso, Peñate-Salas, Xenia, De Miguel-Jiménez, María Dolores, Morillo-Huesca, Macarena, Krogan, Nevan, Chavez-De Diego, Sebastian:
The Prefoldin Complex Regulates Chromatin Dynamics during Transcription Elongation. En: PLoS Genetics. 2013. Vol. 9. Núm. 9. Pag. e1003776-1- e1003776-18 10.1371/journal.pgen.1003776 - Gómez-Herreros, Fernando, De Miguel-Jiménez, María Dolores, Millán-Zambrano, Gonzalo, Peñate-Salas, Xenia, DELGADO-RAMOS, LIDIA, Chavez-De Diego, Sebastian, Muñoz-Centeno, Maria De La Cruz:
One step back before moving forward: Regulation of transcription elongation by arrest and backtracking. En: FEBS Letters. 2012. Vol. 586. Núm. . Pag. 2820-2825 - Gallastegui, Edurne , Millán-Zambrano, Gonzalo, Terme, Jean-michel, Chavez-De Diego, Sebastian, Jordan, Albert:
Chromatin reassembly factors are involved in transcriptional interference promoting HIV latency. En: Journal of Virology. 2011. Vol. 85. Núm. 7. Pag. 3187-3202 10.1128/¿JVI.01920-10 - Haimovich, G, Choder, M, Medina, Da, Causs, Sz, Garber, M, Millán-Zambrano, Gonzalo, Barkai, O, Perez-ortín, Jose Enrique, Darzacq, X:
G .Haimovich, D.A. Medina, S.Z. Causs, M. Garber, G. Millán-Zambrano, O. Barkai, S. Chávez, J.E. Pérez-Ortín, X. Darzacq, M. Choder. En: Cell. . Vol. 153. Núm. 6. Pag. 1000-1011 Genes expresión is circular: factors for mRNA degradation also foster mRNA síntesis
Aportaciones a Congresos: - Payán-Bravo, Laura, Peñate-Salas, Xenia, Millán-Zambrano, Gonzalo, Jimeno-González, Silvia, Gerkhe, Jason, Carey, Michael, J.C. Reyes, Chavez-De Diego, Sebastian:
Contribution of prefoldin to mRNA synthesis in bith yeast and human cells. Ponencia en Congreso. Congreso de la Red Española de RNA. Madrid. 2017 - Payán-Bravo, Laura, Peñate-Salas, Xenia, Millán-Zambrano, Gonzalo, Jimeno-González, Silvia, Gerkhe, Jason, Carey, Michael, J.C. Reyes, Chavez-De Diego, Sebastian:
Prefoldin contributes to transcription elongation in both yeast and human cells. Comunicación en congreso. MOLECULAR CHAPERONES IN CÁNCER. Madrid, Spain. 2017 - Peñate-Salas, Xenia, Millán-Zambrano, Gonzalo, Jordán-pla, Antonio, Puerto - Camacho, Pilar, Rodríguez-ortíz, Beatriz, Chavez-De Diego, Sebastian:
Nuclear Prefoldin interacts with the INO80 chromatin-remodelling complex. Poster en Congreso. Workshop on Chaperones in the Maintenance of Cellular Proteostasis. Baeza, - Baeza (Jaén), España. 2016 - Gutierrez-Pozo, Gabriel, Millán-Zambrano, Gonzalo, Peñate-Salas, Xenia, Chavez-De Diego, Sebastian:
Contribution of TFIIS to nucleosome positioning revealed by improved MNase-seq. Ponencia en Congreso. XXXIX Congreso de la Sociedad Española de Bioquímica y Biología Molecular. - Salamanca, España. 2016 - Gómez-Herreros, Fernando, Cruz-Diaz, Jesus De La, Holstage, Frank, Chavez-De Diego, Sebastian, Margaritis, Thanasis, Rodríguez-galán, Olga, Pelechano, Vicent, Begley, Victoria, Millán-Zambrano, Gonzalo, Morillo-Huesca, Macarena, Muñoz-Centeno, Maria De La Cruz, Pérez-ortín, José E:
Spt6-mediated regulation of transcription elongation is essential for the feedback control of ribosome biogenesis. Poster en Congreso. EMBO Conference Series: Gene Transcription in Yeast: From chromatin to RNA and back. San Feliu de Guixols, España. 2016 - Jordán-pla, Antonio, De Miguel-Jiménez, María Dolores, Gupta, Ishaan , Millán-Zambrano, Gonzalo, Peñate-Salas, Xenia, Steinmetz, Lars, Pelechano, Vicent, Pérez-ortín, Jose E, Chavez-De Diego, Sebastian:
RNA polymerase II backtracking is globally regulated throughout the transcription cycle and contributes to RNA polymerase II processivity. Comunicación en congreso. Systems biology: global regulation of gene expression. Rio Grande, Puerto Rico. 2015 - De Miguel-Jiménez, María Dolores, Peñate-Salas, Xenia, Medina, Daniel, Jordán-plá, Antonio, Millán-Zambrano, Gonzalo, Muñoz-Centeno, Maria De La Cruz, Pérez-ortín, José Enrique:
Backtracking prevents RNA polymerase II drop¿off. Poster en Congreso. EMBO conference: Gene transcription in yeast. SANT FELIU DE GUIXOIS, ESPAÑA. 2014 - Gutierrez-Pozo, Gabriel, Millán-Zambrano, Gonzalo, Peñate-Salas, Xenia, Chavez-De Diego, Sebastian:
An improved method to correct sequence bias in nucleosome mapping by micrococcal nuclease digestion. Poster en Congreso. EMBO conference: Gene transcription in yeast. SANT FELIU DE GUIXOIS, ESPAÑA. 2014 - Millán-Zambrano, Gonzalo, Rodríguez-Gil, Alfonso, Peñate-Salas, Xenia, Gehrke, Jason, Carey, Michael, Chavez-De Diego, Sebastian:
Prefoldin: A cytoskeleton player with an unexpected role in chromatin dynamics. Poster en Congreso. EMBO conference: Gene transcription in yeast. SANT FELIU DE GUIXOIS, ESPAÑA. 2014 - Millán-Zambrano, Gonzalo, Rodríguez-Gil, Alfonso, Peñate-Salas, Xenia, De Miguel-Jiménez, María Dolores, Morillo-Huesca, Macarena, Krogan, Nevan, Chavez-De Diego, Sebastian:
THE PREFOLDIN COMPLEX REGULATES CHROMATIN DYNAMYCS DURING TRANSCRIPTION ELONGATION . Poster en Congreso. Mechanisms of Eukaryotic Transcription. Cold Spring Harbor, New York, USA. 2013 - Chavez-De Diego, Sebastian, De Miguel-Jiménez, María Dolores, Medina, Da, Peñate-Salas, Xenia, Millán-Zambrano, Gonzalo, Choder, M, Pérez-ortín, Je:
RNA pol II backtracking is important for the cross-talk between mRNA decay and transcripction.. Ponencia en Congreso. Workshop: "Gene expression as a circular process: cross-talk between transcription and mRNA degradation in eukaryotes¿. Baeza, España. 2013 - Choder, M, Millán-Zambrano, Gonzalo, Chavez-De Diego, Sebastian, Medina, Da, Pérez-ortín, Je, Haimovich, G:
GENE EXPRESSION IS A CIRCULAR SYSTEM. Ponencia en Congreso. Workshop: "Gene expression as a circular process: cross-talk between transcription and mRNA degradation in eukaryotes¿. Baeza, España. 2013 - Peñate-Salas, Xenia, Gutierrez-Pozo, Gabriel, Millán-Zambrano, Gonzalo, Chavez-De Diego, Sebastian:
CHROMATIN AND REGULATION OF TRANSCRIPTION ELONGATION IN RIBOSOMAL PROTEIN GENES. Comunicación en congreso. Gene expression as a circular process: cross-talk between transcription and mRNA degradation in eukaryotes. BAEZA, BAEZA (ESPAÑA) UNIVERSIDAD INTERNACIONAL DE ANDALUCÍA. 2013 - Millán-Zambrano, Gonzalo, Rodríguez-Gil, Alfonso, Peñate-Salas, Xenia, Morillo-Huesca, Macarena, Gerkhe, J, Krogan, Nevan, Carey, M, Chavez-De Diego, Sebastian:
THE PREFOLDIN COMPLEX REGULATES CHROMATIN DYNAMYCS DURING TRANSCRIPTION ELONGATION . Ponencia en Congreso. 26th International Conference on Yeast Genetics and Molecular Biology. Frankfurt, Germany. 2013 - Chavez-De Diego, Sebastian, Gómez-Herreros, Fernando, De Miguel-Jiménez, María Dolores, Millán-Zambrano, Gonzalo, Rodríguez-Gil, Alfonso, Morillo-Huesca, Macarena, Peñate-Salas, Xenia, Muñoz-Centeno, Maria De La Cruz:
REGULATION OF RNA POLYMERASE II TRANSCRIPTION ELONGATION BY ARREST AND BACKTRACKING. Comunicación en congreso. The Second South American Spring Symposium in Signal Transduction and Molecular Medicine . Bariloche - ARGENTINA, November 2012. 2012 - Chavez-De Diego, Sebastian, Peñate-Salas, Xenia, Muñoz-Centeno, Maria De La Cruz, Pérez-ortín, José E., Gómez-Herreros, Fernando, De Miguel-Jiménez, María Dolores, Millán-Zambrano, Gonzalo, Rodríguez-Gil, Alfonso, Morillo-Huesca, Macarena, Jordan, Toni, Pelechano-Ferragud, Vicente, García-martínez, José:
TRANSCRIPTION FACTORS FAVOURING AND PREVENTING RNA POL II BACKTRACKING . Comunicación en congreso. EMBO WORKSHOP ON GENE TRANSCRIPTION IN YEAST. Saint Feliu de Guixols. 2012 - Choder, Mordechai, Darzacq, X., Chavez-De Diego, Sebastian, Pérez-ortín, José Enrique, Haimovich, G., Medina, D., Millán-Zambrano, Gonzalo, Bregman, A., Halel-sharvit, L., Eldad, N., Causse, S., Barkai, O. :
Gene expression is a circular system . Comunicación en congreso. 22nd IUBMB-37th FEBS International Congress of Biochemistry and Molecular Biology . SEVILLA (SPAIN). 2012 - Millán-Zambrano, Gonzalo, Rodríguez-Gil, Alfonso, Morillo-Huesca, Macarena, Muñoz-Centeno, Maria De La Cruz, Chavez-De Diego, Sebastian:
THE PREFOLDIN COMPLEX PLAYS A ROLE IN TRANSCRIPTION ELONGATION . Comunicación en congreso. EMBO Conference on Gene Transcription in Yeast. SAN FELIU DE GIXOLS (GERONA), ESPAÑA. 2012 - Millán-Zambrano, Gonzalo, Rodríguez-Gil, Alfonso, Morillo-Huesca, Macarena, Muñoz-Centeno, Maria De La Cruz, Chavez-De Diego, Sebastian:
A systematic genetic analysis based on the GLAM assay allows the identification of new yeast genes involved in transcription elongation. Poster en Congreso. Transcription elongation in health and disease. LUCCA, ITALY. 2011 - Millán-Zambrano, Gonzalo, Rodríguez-Gil, Alfonso, Morillo-Huesca, Macarena, Muñoz-Centeno, Maria De La Cruz, Chavez-De Diego, Sebastian:
A systematic genetic analysis based on the GLAM assay allows the identification of new yeast genes involved in transcription elongation . Comunicación en congreso. FASEB Summer Research Conference On Transcription Elongation in Health and Disease . Lucca, Italy. 2011 - Millán-Zambrano, Gonzalo, Morillo-Huesca, Macarena, Muñoz-Centeno, Maria De La Cruz, Chavez-De Diego, Sebastian, Rodríguez-Gil, Alfonso:
A SYSTEMATIC GENETIC ANALYSIS BASED ON THE GLAM ASSAY ALLOWS THE IDENTIFICATION OF NEW YEAST GENES INVOLVED IN TRANSCRIPTION ELONGATION. Comunicación en congreso. EMBO CONFERENCE SERIES: FROM FUNCTIONAL GENOMICS TO SYSTEMS BIOLOGY () (.2010.HEIDELBERG (GERMANY)). HEIDELBERG (GERMANY). 2010 - Millán-Zambrano, Gonzalo, Respaldiza-,Iñaki, De Nadal-,Eulâlia, Posas-,Francesc, Muñoz-Centeno, Maria De La Cruz, Chavez-De Diego, Sebastian:
ANÁLISIS DEL POSICIONAMIENTO DE NUCLEOSOMAS MEDIATE PCR CUANTITATIVA: UNA MEJORA METODOLÓGICA. Poster en Congreso. XXXII CONGRESO DE LA SOCIEDAD ESPAÑOLA DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR (32) (32.2009.OVIEDO, ESPAÑA). OVIEDO, ESPAÑA. 2009
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