ROODVELDT , CINTIA

Perfil en ORCID: 0000-0003-4124-8769

Perfil en ResearcherID: I-9118-2014

Perfil en Scopus: 6508154705\

Grupos de Investigación

• TERAPIAS AVANZADAS EN INMUNOMODULACION Y NEUROPROTECCION

Responsable de los siguientes proyectos/ayudas en la US

Proyectos:

• MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF CHAPERONE/¿-SYNUCLEIN COMPLEXES LINKED TO THE IMMUNE IMBALANCE IN PARKINSON¿S DISEASE. ( SAF2012-39720 ).
• IMMUNOREGULATORY RESPONSE INDUCED BY IMMUNIZATION WITH CHAPERONE/ALPHA-SYNUCLEIN COMPLEXES AS A NOVEL APPROACH TO PARKINSON'S DISEASE THERAPY: BASIC O ( CP10/00527 ).
• IMMUNE REGULATION STUDIES BY ALPHA-SYNUCLEIN IN PARKINSON DISEASE. ROLE OF CO-CHAPERONES ( FDF-2010-FEBS ).

Participa los siguientes proyectos/ayudas en la US

Proyectos:

• Signaling kinases and mechanisms of immunoregulation in amyotrophic lateral sclerosis (ALS) ( PID2022-140838OB-I00 - Investigador Principal Consolidado).
• Caracterización Funcional y de los Mecanismos de Acción mediados por la Kinasa de Señalización MOK en la Neuroinflamación asociada a la Esclerosis Lat ( 2019/FARECES/CROODVELT - Investigador Principal Consolidado).
• Caracterización Funcional y de los Mecanismos de Acción mediados por MOK en la Neuroinflamación asociada a Proteinopatías Neurodegenerativas: Escleros ( US-1265227 - Investigador Principal Consolidado).
• Mecanismos Moleculares de una Proteína de la Familia Bet en la Respuesta Neuroinflamatoria Asociada a Proteinopatías Neurodegenerativas ( PY20_01097 - Investigador Principal Consolidado).
• Caracterización Funcional e Intervención de una Nueva Ruta de Señalización de la Neuroinflamación Mediada por Microglia en Esclerosis Lateral Amiotróf ( RTI2018-098432-B-I00 - Investigador Principal Consolidado).
• Development of a novel therapy for the treatment of genetic variants of ¿-synuclein in Parkinson¿s Disease ( RTC-2015-3309-1 - Investigador Principal Consolidado).
• NANOTECNOLOGÍA COMO PLATAFORMA DE DESARROLLO DE INMUNOTERAPIAS MEDIADAS POR NPS FUNCIONALIZADAS CON EL PEPTIDO INTESTINAL VASOACTIVO EN ENFERMEDADES I ( CTS-6928 - Investigador/a).
• ESTUDIO DE LA CAPACIDAD INMUNOREGULADORA DEL PÉPTIDO INTESTINAL VASOACTIVO (VIP) SOBRE CÉLULAS MADRE DERIVADAS DE TEJIDO ADIPOSO (CMDA) EN EL MODELO P ( PS09/02252 - Investigador/a).
• ARE THERE NATURAL AUTOEPITOPE-MIMICHING MELECULES WITH CYTOTOXIC ACTIVITY, CAPABLE OF PREVENTING AUTOIMMUNE DISEASE? A BASIC BIOLOGICAL QUESTION WITH ( SAF2007-29418-E - Investigador/a).

Contratos:

• Towards a therapeutic vaccine for Amyotrophic lateral sclerosis: ALSVac ( 2106/0013 - Investigador/a ).
• PROGRAMAS DE I+D+I ESTRATÉGICOS EN TERAPIA GÉNICA, CELULAR Y NANOMEDICINA. DIRECCION AREA DESARROLLO DE LA PRODUCCIÓN CIENTÍFICA. FUNDACIÓN PÚBLICA AN ( 0013 - Investigador/a ).
• BIOMARCADORES. DESARROLLO Y APLICACIONES EN AGROALIMENTACIÓN Y SANIDAD ( SI-015/07 - Investigador/a ).
• REALIZACIÓN DE PRUEBAS DE CONCEPTO PARA EL ESTUDIO DE LA ACTIVIDAD INMUNOMODULADORA DEL CONDROÍTIN SULFATO. ( 0541/0013 - Investigador/a ).
• DISEÑO E IMPLANTACIÓN DE PROGRAMAS Y PROYECTOS DE INNOVACIÓN E INVESTIGACIÓN BIOMÉDICA DEL SISTEMA SANITARIO PÚBLICO DE ANDALUCIA ( 0014/0013 - Investigador/a ).
• Programa 'Ramón y Cajal' 2017, Ministerio de Ciencia e Innovación de España ( RYC-2017-23127 - Investigador/a ).
• Programa 'Atracción de Talento', Personal Docente Investigador (Plan Propio de la Universidad de Sevilla) ( - Investigador/a ).
• Programa Investigadora 'Miguel Servet II', Instituto de Salud Carlos III (ISCIII) ( CPII16/58 - Investigador/a ).

Ayudas:

• Pruebas de Concepto Preclínicas: Estudio de la Respuesta Mediada Por Células T. ( EF-1030-2012 - Investigador/a ).
• FINANCIACION DE LOS GRUPOS UNIVERSITARIOS DE INVESTIGACION Y DESARROLLO TECNOLOGICO DE LA COMUNIDAD AUNTONOMA ANDALUZA ( HUM-321 - Investigador/a ).

Publicaciones

Libros:

• Roodveldt-, Cintia, Outeiro, Tiago F, Braun, Janice E:
  Molecular chaperones and Neurodegeneration. Frontiers in Neurology. 2017. ISBN

Capítulo de Libros:

• Roodveldt-, Cintia, Labrador-Garrido, Adahir, Izquierdo-, Guillermo, Fernández-Montesinos, Rafael, Pozo-Pérez, David:
  ALPHA-SYNUCLEIN AND THE IMMUNE SYSTEM IN PARKINSON'S DISEASE.. Pag. 57 - 76. En: Towards New Therapies for Parkinson's Disease (Ed. Intech, Vienna, Austria). INTECH - OPEN ACCESS PUBLISHER. 2011. ISBN 978-953-307-463-4
• Labrador-Garrido, Adahir, Bertoncini, Carlos W., Roodveldt-, Cintia:
  THE HSP70 CHAPERONE SYSTEM IN PARKINSON'S DISEASE. Pag. 221 - 246. En: Etiology and Pathophysiology of Parkinson's Disease (Ed. Intech, Vienna, Austria). INTECH - OPEN ACCESS PUBLISHER. 2011. ISBN 978-953-307-462-7
• Aharoni-,A, Roodveldt-, Cintia, GRIFFITHS-,AD, Tawfik-, Ds:
  HIGH-THROUGHPUT SCREENS AND SELECTIONS OF ENZYME ENCODING GENES. Pag. 163 - 179. En: ENZYME ASSAYS: HIGH-THROUGHPUT SCREENING, GENETIC SELECTION AND FINGERPRINTING. Wiley. 2005. ISBN

Publicaciones en Revistas:

• Pérez-Cabello, Jesús Á., Lall, Deepti, Baloh, Robert H., Martínez, Salvador, Miyata, Yoshihiko, Tartaglia, Gian G., Sawarkar, Ritwick, García-Domínguez, Mario, Pozo-Pérez, David, Roodveldt-, Cintia, Silvera , Lucía, Muñoz-Franco, Jaime, CAPILLA-GONZÁLEZ, VIVIAN, Armaos, Alexandros, Gomez, Maria, Garcia, Raquel, Yap, Xin Wen, María M. Leal-Lasarte:
  MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS. En: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2023. Vol. 120. Núm. 28. Pag. e2302143120- 10.1073/pnas.2302143120
• María M. Leal-Lasarte, Mannini, Benedetta, Chiti, Fabrizio, Vendruscolo, Michele, Dobson, Christopher, Roodveldt-, Cintia, Pozo-Pérez, David:
  Distinct responses of human peripheral blood cells to different misfolded protein oligomers. En: Immunology: the journal of cells, molecules, system and technologies. 2021. Vol. 164. Núm. 2. Pag. 358-371 10.1111/imm.13377
• Garcia, Raquel, Martín, Laura, Blanca, Laura, Pérez-Cabello, Jesús Á., García-garcía, Raquel:
  Immune Signaling Kinases in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). En: International Journal of Molecular Sciences. 2021. Vol. 22. Núm. 24. Pag. 13280- 10.3390/ijms222413280
• Mannini, Benedetta, Chiti, Fabrizio, Dobson, Christopher M., Roodveldt-, Cintia, Vecchi, Giulia, Labrador-Garrido, Adahir, Fabre, B., Fani, Giulia, Muñoz-Franco, Jaime, Lilley, K., Pozo-Pérez, David, Vendruscolo, Michele:
  Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers.. En: ACS Chemical Neuroscience. 2019. Vol. 10. Núm. 8. Pag. 3464-3478
• Villadiego-Luque, Francisco Javier, Labrador-Garrido, Adahir, Leal-lasarte, M. Magdalena, Muñoz-Franco, Jaime, De Genst, Erwin J., Dobson, Christopher M., Pozo-Pérez, David, Toledo-Aral, Juan José, Roodveldt-, Cintia:
  Immunization with alpha-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model.. En: Glia. 2018. Vol. 66. Núm. 1. Pag. 191-205 10.1002/glia.23237
• Leal-lasarte, M. Magdalena, Muñoz-Franco, Jaime, Labrador-Garrido, Adahir, Pozo-Pérez, David, Roodveldt-, Cintia:
  Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia.. En: The FASEB Journal. 2017. Vol. . Núm. . Pag. - 10.1096/fj.201601163R
• Sot, B, Rubio-muñoz, A, Leal-quintero, A, Martínez-sabaneo, J, Marcela, M, Roodveldt-, Cintia, Valpuesta, Jm:
  The chaperonin CCT inhibits assembly of alpha-synuclein amyloid fibrils by a specific, conformation-dependent interaction.. En: Scientific Reports. 2017. Vol. . Núm. . Pag. - 10.1038/srep40859
• Johnson, Ian P, Roodveldt-, Cintia:
  Commentary: Immunochemical Markers of the Amyloid Cascade in the Hippocampus in Motor Neuron Diseases.. En: Frontiers in Neurology. 2017. Vol. . Núm. . Pag. - 10.3389/fneur.2017.00105
• Labrador-Garrido, Adahir, Jackson, Sophie E, Pozo-Pérez, David, Roodveldt-, Cintia, CEJUDO-GUILLÉN, MARTA, Daturpalli, Soumya, Leal, Maria M, Klippstein-Martín, Rebecca, De Genst, Erwin J, Villadiego-Luque, Francisco Javier, Toledo-Aral, Juan José, Dobson, Christopher M:
  Chaperome screening leads to identification of Grp94/Gp96 and FKBP4/52 as modulators of the a-synuclein¿elicited immune response. En: The FASEB Journal. 2016. Vol. 30. Núm. 2. Pag. 564-577 10.1096/fj.15-275131
• Caballero-hernández, Diana, Toscano, Miguel, CEJUDO-GUILLÉN, MARTA, García-Martín, María Luisa, Lopez-Enriquez, Soledad, Muñoz-Franco, Jaime, Quintana, Francisco J., Roodveldt-, Cintia, Pozo-Pérez, David:
  The 'Omics' of Amyotrophic Lateral Sclerosis.. En: Trends in molecular medicine. 2016. Vol. 22. Núm. 1. Pag. 53-67 10.1016/j.molmed.2015.11.001
• Chen, Sw, Valpuesta, Jm, Dobson, Cm, Cremades, N, Drakulic, S, Roodveldt-, Cintia:
  Structural characterization of toxic oligomers that are kinetically trapped during ¿-synuclein fibril formation.. En: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2015. Vol. . Núm. . Pag. - 10.1073/pnas.1421204112
• Labrador-Garrido, Adahir, Pozo-Pérez, David, Roodveldt-, Cintia, CEJUDO-GUILLÉN, MARTA, Klippstein-Martín, Rebecca, De Genst, Erwin J, Tomás-Gallardo, Laura, Leal, Maria M, Villadiego-Luque, Francisco Javier, Toledo-Aral, Juan José, Dobson, Christopher M:
  Chaperoned amyloid proteins for immune manipulation: a-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype. En: Immunity, Inflammation & Disease. 2014. Vol. 2. Núm. 4. Pag. 226-238 10.1002/iid3.39
• Tomás-Gallardo, Laura, Labrador-Garrido, Adahir, David, Pozo, Roodveldt-, Cintia, Cejudo-guillen, Marta, Klippstein, Rebecca, De Genst, Erwin J, Tomas-gallardo, Laura, Leal, Maria M, Villadiego, Javier, Toledo-aral, Juan J, Dobson, Christopher M:
  Chaperoned amyloid proteins for immune manipulation: alpha-synuclein/Hsp70 shifts immunity towards a modulatory phenotype. En: Immunity, Inflammation & Disease. 2014. Vol. . Núm. . Pag. - 10.1002/iid3.39
• Roodveldt-, Cintia, Pozo-Pérez, David, Labrador-Garrido, Adahir, Fernández-Montesinos, Rafael, Lachaud, Christian C, Guilliams, Tim, Fernandez-montesinos, Rafael, Benitez-Rondan, Alicia, Delgado, Mario, Dobson, Christopher M:
  Preconditioning of microglia by alpha-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.. En: PLoS One. 2013. Vol. 8. Núm. 11. Pag. e79160-
• Aprile, Francesco A, Cremades, Nunilo, Dhulesia, Anne, Stengel, Florian, Roodveldt-, Cintia, Benesch, Justin L, Tortora, P, Robinson, Carol P, Salvatella, Xavier, Dobson, Christopher M:
  Hsp70 Oligomerization Is Mediated By An Interaction Between The Interdomain Linker And The Helical Lid Of The Substrate-Binding Domain. En: PLoS One. 2013. Vol. 8. Núm. 6. Pag. e67961-
• Roodveldt-, Cintia, Andersson, August, De Genst, Erwin J., Labrador-Garrido, Adahir, Buell, Alex K., Dobson, Christopher M., Tartaglia, Gian G., Vendruscolo, Michele:
  A Rationally Designed Six-Residue Swap Generates Comparability in the Aggregation Behavior of ¿-Synuclein and ß-Synuclein.. En: Biochemistry-US. 2012. Vol. 51. Núm. 44. Pag. 8771-8778
• Mannini, Benedetta, Relini, A., Kampinga, Harm H., Dobson, Christopher M., Wilson, Mark R., Cecchi, C., Chiti, Fabrizzio, Cascella, R., Zampagni, M., Van Waarde-verhagen, M., Meehan, Sarah, Roodveldt-, Cintia, Campioni, Silvia, Boninsegna, M., Penco, A.:
  Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers.. En: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2012. Vol. 109. Núm. 31. Pag. 12479-12484
• Roodveldt-, Cintia, Labrador-Garrido, Adahir, Caro-Moreno, Marta, Gonzalez-Rey, Elena, Caro, Marta, Fernández-Montesinos, Rafael, Lachaud-, Christian, Waudby A., Christopher, Delgado-Mora, Mario, Dobson, Christopher M., Pozo-Pérez, David:
  Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and parkinson¿s disease-linked mutants.. En: PLoS One. 2010. Vol. 5. Núm. 10. Pag. E13481-E13481
• Roodveldt-, Cintia, Bertoncini-,Cw, Christodoulou-,J, Dobson-,C.M., Andersson-,A, Van Der Goot-,At, Hsu-, S.T., Fernández-Montesinos, Rafael, De Jong-,J, Van Ham-,Tj, Nollen-,Ea, Pozo-Pérez, David:
  CHAPERONE PROTEOSTASIS IN PARKINSON'S DISEASE: STABILIZATION OF THE HSP70/ALPHA-SYNUCLEIN COMPLEX BY HIP. En: EMBO Journal. 2009. Vol. 28. Núm. . Pag. 3758-3770
• Roodveldt-, Cintia, Christodoulou-,J, Dobson-,Cm:
  IMMUNOLOGICAL FEATURES OF ALPHA-SYNUCLEIN IN PARKINSON'S DISEASE. En: Journal of Cellular and Molecular Medicine. 2008. Vol. 12. Núm. 5B. Pag. 1820-1829
• Khersonsky-,O, Roodveldt-, Cintia, Tawfik-, Ds:
  ENZYMe PROMISCUITY: EVOLUTIONARY AND MECHANISTIC ASPECTs. En: Current Opinion in Chemical Biology. 2006. Vol. 10. Núm. . Pag. 498-508
• Afriat-,L, Roodveldt-, Cintia, Manco-,G, Tawfik-, Ds:
  The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase. En: Biochemistry (Moscow). 2006. Vol. 45. Núm. 46. Pag. 13677-13686
• Aharoni-,A, Roodveldt-, Cintia, Tawfik-, Ds:
  DIRECTED EVOLUTION FOR HIGH EXPRESSION AND STABILITY OF HETEROLOGOUS PROTEINS. En: Current Opinion in Structural Biology. 2005. Vol. . Núm. . Pag. 50-56
• Roodveldt-, Cintia, Tawfik-, Ds:
  SHARED PROMISCUOUS ACTIVITIES AND EVOLUTIONARY FEATURES IN VARIOUS MEMBERS OF THE AMIDOHYDROLASE SUPERFAMILY. En: Biochemistry (Moscow). 2005. Vol. . Núm. . Pag. 12728-12736
• Roodveldt-, Cintia, Tawfik-, Ds:
  DIRECTED EVOLUTION OF PHOSPHOTRIESTERASE FROM PSEUDOMONAS DIMINUTA FOR OVER-EXPRESSION IN E. COLI RESULTS IN STABILIZATION OF THE METAL-FREE STATE. En: Protein Engineering Design & Selection. 2005. Vol. . Núm. . Pag. 51-58
• Marcipar-,Is, Roodveldt-, Cintia, Corradi-,G, Cabeza-,Ml, Brito-,Me, Marcipar-,Aj, Silber-,Am:
  IMPROVEMENT OF TRYPANOSOMA CRUZI DIAGNOSIS ROUTINE FOR CHAGAS' DISEASE BY USING THE FULL-LENGTH RECOMBINANT CALFLAGIN AND ITS C-FRAGMENT. En: Journal of Clinical Microbiology. 2005. Vol. . Núm. . Pag. 5498-5503
• Aharoni-,A, Gaidukov-,L, Khersonsky-,O, Mcq Gould-,S, Roodveldt-, Cintia, Tawfik-, Ds:
  THE 'EVOLVABILITY' OF PROMISCUOUS PROTEIN FUNCTIONS. En: Nature Genetics. 2005. Vol. . Núm. . Pag. 73-76
• Marcipar-,Is, Welchen-,E, Roodveldt-, Cintia, Marcipar-,Aj, Silber-,Am:
  PURIFICATION OF THE 67-KDA LECTIN-LIKE GLYCOPROTEIN OF TRYPANOSOMA CRUZI, LLGP-67, AND ITS EVALUATION AS A RELEVANT ANTIGEN FOR THE DIAGNOSIS OF HUMAN. En: Fems Microbiology Letters. 2003. Vol. 220. Núm. . Pag. 149-154
• Silber-,Am, Marcipar-,Is, Roodveldt-, Cintia, Cabeza Meckert-,P, Laguens-,R, Marcipar-,Aj:
  TRYPANOSOMA CRUZI: IDENTIFICATION OF A GALACTOSE-BINDING PROTEIN THAT BINDS TO CELL SURFACE OF HUMAN ERYTHROCYTES AND IS INVOLVED IN CELL INVASION BY . En: Experimental Parasitology. 2002. Vol. . Núm. . Pag. 217-225

Aportaciones a Congresos:

• Silvera , Lucía, Roodveldt-, Cintia, Pozo-Pérez, David, Garcia, Raquel, Pérez-Cabello, Jesús Á., Sola, Alejandro, Martín-Montalvo-Sánchez, Alejandro:
  Gene editing reveals ADNP protein (Activity-Dependent Neuroprotective Protein) physiological roles in microglia and its potential implications in neur. Poster en Congreso. European Network to Cure ALS ¿ ENCALS meeting. Barcelona, España. 2023
• Silvera , Lucía, Sola, Alejandro, Martín-Montalvo-Sánchez, Alejandro, Roodveldt-, Cintia, Pozo-Pérez, David, Garcia, Raquel, CEJUDO-GUILLÉN, MARTA, Pérez-Cabello, Jesús Á.:
  Molecular and cellular insights into VIP/ADNP neuropeptide regulation of ALS progression. Poster en Congreso. Gordon Research Conference (GRC) in 'ALS and Related Motor Diseases. Les Diablerets, Suiza. 2023
• Pérez-Cabello, Jesús Á., Lall, Deepti, Baloh, Robert H., Martínez, Salvador, Miyata, Yoshihiko, Tartaglia, Gian G., Sawarkar, Ritwick, García-Domínguez, Mario, Pozo-Pérez, David, Roodveldt-, Cintia, Silvera , Lucía, Muñoz-Franco, Jaime, CAPILLA-GONZÁLEZ, VIVIAN, Armaos, Alexandros, Gomez, Maria, Garcia, Raquel, Yap, Xin Wen, María M. Leal-Lasarte:
  MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS. Poster en Congreso. Amyotrophic Lateral Sclerosis (ALS) & Motor Neuron Disease. LEs Diablerets (Suiza). 2023
• Garcia, Raquel, Silvera , Lucía, Tebaldi, Enrico, Rodríguez-martín, Araceli, Tejada-moreno, Daniel, Sola, Alejandro, Martín-Montalvo-Sánchez, Alejandro, Pozo-Pérez, David, Roodveldt-, Cintia:
  Role of MOK kinase in microglial TBK1/type-1 IFN pathway and mitochondrial function. Poster en Congreso. ENCALS Annual Meeting. . BARCELONA. 2023
• Pérez-Cabello, Jesús Á., Pozo-Pérez, David, Sawarkar, Ritwick, Roodveldt-, Cintia, Silvera , Lucía, Garcia, Raquel, Gomez, Maria, Armaos, Alexandros, María M. Leal-Lasarte, Blanca, Laura, Vernon, Sabine, Tartaglia, Gian G.:
  Cell signaling and gene expression regulation in microglia under TDP-43 aggregation. Poster en Congreso. Protein Homeostasis in Health & Disease, Cold Spring Harbor Laboratory. Cold Spring Harbor, - NEW YORK - ESTADOS UNIDOS, EEUU. 2022
• Gómez-lima, M., María M. Leal-Lasarte, Muñoz-Franco, Jaime, González-Sánchez, Zaira Isabel, Armaos, A., Tartaglia, Gg., Pozo-Pérez, David, Roodveldt-, Cintia:
  A role for MOK protein kinase in neuroinflammation linked to amyotrophic lateral sclerosis. Poster en Congreso. EMBO Workshop on "ProteinQuality Control: from Mechanisms to Disease". Costa de la Calma (Mallorca). 2019
• Pozo-Pérez, David, Roodveldt-, Cintia, María M. Leal-Lasarte, González-Sánchez, Zaira Isabel, CABALLERO-HERNÁNDEZ, DIANA ELIA, CEJUDO-GUILLÉN, MARTA, Gómez-lima, María, Muñoz-Franco, Jaime:
  New insights into the role of innate immune regulation and altered metabolic homeostasis in amyotrophic lateral sclerosis (ALS): Implications for trea. Comunicación en congreso. XV Congreso Internacional De Investigacio¿n Cienti¿fica . Santo Domingo. 2019
• Gómez-lima, M., María M. Leal-Lasarte, Muñoz-Franco, Jaime, González-Sánchez, Zaira Isabel, Armaos, A., Tartaglia, Gg., Pozo-Pérez, David, Roodveldt-, Cintia:
  Implications of MOK protein kinase in neuroinflammation linked to ALS. Poster en Congreso. Gordon Research Conference (GRC) on `Amyotrophic Lateral Sclerosis (ALS) and Related Motor Neuron Diseases¿. Mt. Snow, VT, EE.UU. 2019
• Roodveldt-, Cintia:
  Protein aggregation and neuroinflammation in neurodegenerative misfolding disease. Conferencias impartidas en Congreso. EMBO Conference on `Protein Quality Control: From Mechanisms to Disease¿. Tramontana, España. 2019
• Roodveldt-, Cintia:
  TDP-43 misfolding and neuroinflammation in ALS.. Conferencias impartidas en Congreso. V International Conference of the Centre for Misfolding Diseases.. Trasmina, - Bolonia, Italia. 2018
• Labrador-Garrido, Adahir, Villadiego-Luque, Francisco Javier, De Genst, Erwin J., Dobson, Christopher M., Pozo-Pérez, David, Toledo-Aral, Juan José, Roodveldt-, Cintia:
  Vaccination with alpha-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic model of Parkinson¿s disease.. Poster en Congreso. Alpha-synuclein and Parkinson¿s Disease Conference: Lessons from the past 20 years.. Barcelona, España. 2017
• Roodveldt-, Cintia:
  Immunization with heat-shock protein-`chaperoned¿ ¿-synuclein as a novel immunotherapeutic strategy against Parkinson¿s Disease. Conferencias impartidas en Congreso. International Congress on Neuroimmunology & Therapeutics. California, California, San Francisco, USA. 2016
• Roodveldt-, Cintia:
  Vaccination with a Grp94/alpha-synuclein combination as a novel approach for immunotherapy against Parkinson¿s disease. Poster en Congreso. Cold Spring Harbor Laboratory Meetings on `Protein Homeostasis in Health and Disease¿. COLD SPRING HARBOR, EE.UU. 2016
• Leal-lasarte, M. Magdalena, Labrador-Garrido, Adahir, Pozo, David, Roodveldt-, Cintia:
  Exogenous TDP-43 species are internalized by microglia and elicit different immune profiles dependent on co-stimulating molecules. Poster en Congreso. Cold Spring Harbor Laboratory Meetings on `Protein Homeostasis in Health and Disease¿. COLD SPRING HARBOR, EE.UU. 2016
• Roodveldt-, Cintia:
  Molecular chaperones and immunity in neurodegenerative proteinopathies. Sesión plenaria en Congreso. Chaperones in the Maintenance of Cellular Proteostasis. - Baeza (Jaén), España. 2016
• Mannini, Bendita, Labrador-Garrido, Adahir, Vecchi, Giulia, Fabre, B, Pozo-Pérez, David, Dobson, Christopher M., Chiti, Fabrizio, Vendruscolo, Michele, Roodveldt-, Cintia:
  Immune response triggered by aberrant protein oligomers in microglial cells. Poster en Congreso. Cold Spring Harbor Laboratory Meetings on `Protein Homeostasis in Health and Disease¿. COLD SPRING HARBOR, EE.UU. 2016
• Roodveldt-, Cintia:
  Molecular chaperones and immunity in neurodegenerative proteinopathies. Sesión plenaria en Congreso. Chaperones in the Maintenance of Cellular Proteostasis. - Baeza (Jaén), España. 2016
• Roodveldt-, Cintia:
  Chaperones and immunity in protein misfolding diseases. Conferencias impartidas en Congreso. IV International Conference of the Centre for Misfolding Diseases. Sevilla, España. 2016
• Roodveldt-, Cintia:
  Molecular chaperones and immunity in neurodegenerative proteinopathies. Sesión no plenaria en Congreso. Chaperones in the Maintenance of Cellular Proteostasis. - Baeza (Jaén), España. 2016
• Roodveldt-, Cintia:
  Chaperones and immunity in protein misfolding diseases. Conferencias impartidas en Congreso. IV International Conference of the Centre for Misfolding Diseases. Sevilla. 2016
• Mannini, Bendetta, Labrador-Garrido, Adahir, Leal, Maria M, Cejudo-guillen, Marta, Chiti, Fabrizio, Pozo, David, Roodveldt-, Cintia:
  ¿Immune response triggered by aberrant protein oligomers in microglial cells¿. Poster en Congreso. EMBL Conference `Microglia: guardian of the brain¿. Heidelberg, Germany.. . 2014
• Roodveldt-, Cintia, Labrador-Garrido, Adahir, Gonzalez-Rey, Elena, Lachaud-, Christian, Guilliams, Tim, Fernández-Montesinos, Rafael, Delgado-Mora, Mario, Dobson, Chistopher M., Pozo-Pérez, David:
  Preconditioning of microglia with Parkinson-linked alpha-synuclein affects the response induced by Toll-like receptor (TLR) stimulation. Poster en Congreso. 11th International Congress of Neuroimmunology. Boston, MA (USA). 2012
• Roodveldt-, Cintia, Labrador-Garrido, Adahir, Gonzalez-Rey, Elena, Caro-,Marta, Lachaud-, Christian, Waudby-,Christopher, Delgado-Mora, Mario, Dobson-,Christopher M., Pozo-Pérez, David:
  GLIAL INNATE IMMUNITY GENERATED BY NON-AGGREGATED ALPHA-SYNUCLEIN: DIFFERENCES BETWEEN WILD-TYPE AND PARKINSON DISEASE-LINKED MUTANTS.. Poster en Congreso. 10TH INTERNATIONAL CONGRESS OF NEUROIMMUNOLOGY (10) (10.2010.BARCELONA). . 2010
• Roodveldt-, Cintia, Bertoncini-,Cw., Andersson-,A., Van Der Goot-,A.T., Nollen-,E.A.A., Fernández-Montesinos, Rafael, Pozo-Pérez, David, Christodoulou-,J., Dobson-,C.M:
  MOLECULAR MECHANISMS IN PARKINSON'S DISEASE: THE HSP70/ALPHA-SYNUCLEIN CROSSTALK. Poster en Congreso. XXXII CONGRESO DE LA SOCIEDAD ESPAÑOLA DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR (32) (32.2009.OVIEDO, ESPAÑA). OVIEDO, ESPAÑA. 2009
• Labrador-Garrido, Adahir, Fernández-Montesinos, Rafael, Gonzalez-Rey-, Elena, Delgado-Mora, Mario, Pozo-Pérez, David, Roodveldt-, Cintia:
  MODULATION OF THE INNATE RESPONSE BY ALPHA-SYNUCLEIN AND RELATED MUTANTS: CHARACTERIZATION OF CHEMOKINES, PROINFLAMMATORY AND REGULATORY CYTOKINES. Poster en Congreso. XXXII CONGRESO DE LA SOCIEDAD ESPAÑOLA DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR (32) (32.2009.OVIEDO, ESPAÑA). OVIEDO, ESPAÑA. 2009
• Roodveldt-, Cintia:
  ALPHA-SYNUCLEIN AGGREGATION AND THE MOLECULAR ORIGINS OF PARKINSON'S DISEASE. Conferencias impartidas en Congreso. ESTUDIANTES DE POSTGRADO Y PERSONAL CIENTIFICO-INVESTIGADOR. FACULTAD DE MEDICINA, UNIVERSIDAD DE CADIZ. 2009
• Roodveldt-, Cintia:
  HSP70, ALPHA-SYNUCLEIN, AND THE MOLECULAR ORIGINS OF PARKINSON'S DISEASE. Conferencia Congreso no publicada. GUEST SEMINARS - CENTRO NACIONAL DE BIOTECNOLOGÍA (CNB), MADRID. () (.2009.CENTRO NACIONAL DE BIOTECNOLOGÍA (CNB), MADRID). CENTRO NACIONAL DE BIOTECNOLOGÍA (CNB), MADRID. 2009
• Labrador-Garrido, Adahir, Roodveldt-, Cintia:
  DIFFERENTIAL MODULATION OF THE NEUROINFLAMMATORY RESPONSE BY WILD-TYPE AND MUTANT ALPHA-SYNUCLEIN. Poster en Congreso. YOUNG SCIENTIST FORUM FEBS () (.2009.PRAGUE). PRAGUE. 2009
• Labrador-Garrido, Adahir, Fernández-Montesinos, Rafael, Gonzalez-Rey-, Elena, Delgado-, M, Pozo-Pérez, David, Roodveldt-, Cintia:
  DIFFERENTIAL MODULATION OF THE NEUROINFLAMMATORY RESPONSE BY WILD-TYPE AND MUTANT ALPHA-SYNUCLEIN. Comunicación en congreso. FEBS YOUNG SCIENTISTS FORUM () (.2009.PRAGA, REPÙBLICA CHECA). PRAGA, REPÙBLICA CHECA. 2009
• Roodveldt-, Cintia:
  PARKINSON'S DISEASE: MECHANISM OF HSP70 INHIBITION OF ALPHA-SYNUCLEIN AMYLOID FORMATION. Conferencias impartidas en Congreso. ESTUDIANTES DE POSTGRADO Y PERSONAL CIENTIFICO-INVESTIGADOR. INSTITUTO DE PARASITOLOGIA Y BIOMEDICINA "LOPEZ NEYRA" (IPBLN), (CSIC), GRANADA, ESPAÑA. 2008
• Roodveldt-, Cintia:
  HSP70 AND SYNUCLEIN INTEREACTIONS: NEW INSIGHTS INTO THE MOLECULAR ORIGIN OF PARKINSON'S DISEASE. Conferencias impartidas en Congreso. ESTUDIANTES DE POSTGRADO Y PERSONAL CIENTIFICO-INVESTIGADOR. FACULTAD DE BIOQUIMICA MEDICA Y BIOLOGIA MOLECULAR, UNIVERSIDAD DE SEVILLA, ESPAÑA. 2008
• Roodveldt-, Cintia, Andersson-,A, Bertoncini-,Cw, Christodoulou-,J, Pozo-Pérez, David, Dobson-,Cm:
  MOLECULAR INSIGHTS INTO THE ANTI-AGGREGATION ACTIVITY OF HSP70 WITH ALPHA-SYNUCLEIN. Poster en Congreso. EMBO WORKSHOP ON PROTEIN FOLDING AND CHAPERONES () (.2007.TOMAR, PORTUGAL). . 2007
• Roodveldt-, Cintia, Christodoulou-,J, Dobson-,Cm:
  MECHANISM OF THE HSP70¿S INHIBITION OF ALPHA-SYNUCLEIN FIBRILLATION.. Poster en Congreso. FEBS ANNUAL MEETING () (.2007.VIENA, AUSTRIA). VIENA, AUSTRIA. 2007
• Roodveldt-, Cintia:
  HOW ENZYMES ACQUIRE NEW FUNCTIONS: LEARNING FROM DIRECTED EVOLUTION. Conferencias impartidas en Congreso. ESTUDIANTES DE POSTGRADO Y PERSONAL CIENTIFICO-INVESTIGADOR. PALACIO DE CONGRESOS Y EXPOSICIONES, GRANADA, ESPAÑA. 2006
• Roodveldt-, Cintia, Tawfik-, Ds:
  EVOLUTION OF THE PROMISCUOUS ACTIVITIES IN MEMBERS OF THE AMIDOHYDROLASE SUPERFAMILY OF ENZYMES. Poster en Congreso. GORDON RESEARCH CONFERENCE (GRC): ENZYMES AND METABOLIC PATHWAYS () (.2004.MERIDEN (NH), EEUU). MERIDEN (NH), EEUU. 2004
• Roodveldt-, Cintia:
  Docencia impartida- BIOQUIMICA Y BIOLOGIA MOLECULAR BASICA, Universidad de Sevilla. Conferencias impartidas en Congreso. ESTUDIANTES DE POSTGRADO Y PERSONAL CIENTIFICO-INVESTIGADOR. .

Patentes:

• Roodveldt-, Cintia, Leal Lasarte, M. Magdalena, Muñoz-Franco, Jaime, Pozo-Pérez, David:
  Agentes moduladores de MOK para el tratamiento de enfermedades con componente inflamatorio, enfermedades neurodegenerativas, enfermedades inflamatoria. Patente de invención, Propiedad industrial. Solicitud: 21/03/2017
• Roodveldt-, Cintia, Márquez Infante, Celedonio, Pozo-Pérez, David, CEJUDO-GUILLÉN, MARTA, Lopez-Enriquez, Soledad:
  Biomarcadores para la Esclerosis Lateral Amiotrófica (ELA). Patente de invención, Propiedad industrial. Solicitud: 15/09/2015
• Roodveldt-, Cintia, Labrador-Garrido, Adahir, Pozo, David:
  `Combinaciones de proteínas agregantes y chaperonas moleculares para el tratamiento de proteinopatías o enfermedades conformacionales¿. Patente de invención, Propiedad industrial. Solicitud: 11/09/2013

Tesis dirigidas y co-dirigidas:

• :
  Novel molecular mechanisms and signaling pathways of microglial responses in amyotrophic lateral sclerosis (ALS) . Tesis Doctoral. 2018
• :
  Alpha-Synuclein and Immune System Crosstalk in Parkinson¿s Disease: Therapeutic approaches of its Modulation by Molecular Chaperones. Tesis Doctoral. 2017
• :
  Crosstalk between peripheral and central immunity in amyotrophic lateral sclerosis (ALS).. Tesis Doctoral. 2016