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VEGA MORENO, FRANCISCO MPerfil en ORCID: 0000-0002-9015-864X Perfil en ResearcherID: C-4678-2008 Perfil en Scopus: 57190945608\ Grupos de Investigación - FISIOPATOLOGÍA DE CÉLULAS MADRE NEURALES
Responsable de los siguientes proyectos/ayudas en la USParticipa los siguientes proyectos/ayudas en la USProyectos: - Identification of Regulators of breast cancer cell invasion and migration [Grant 2008MayPR13] ( 2008MayPR13 - Investigador/a).
Contratos: - Marie Curie Individual Research contract ( - Investigador/a ).
Ayudas: - Jornada sobre Alergia e Intolerancias alimentarias frecuentes en la población infantil ( - Participante ).
- Ayuda de Divulgación científica 2020 ( - Participante ).
- Ayuda para actividades de Divulgación científica ( - Participante ).
PublicacionesCapítulo de Libros: - Francisco M Vega, Reymond, Nicolas, Ridley, Anne:
RhoC. Pag. 1664 - 1668. En: Encyclopedia of Signalling Molecules. Springer. 2018. ISBN 978-3-319-67198-7 - Vega-Moreno, Francisco Manuel, Reymond, Nicolas, Ridley, Anne J.:
RhoC. Pag. 1664 - 1668. En: Encyclopedia of Signalling Molecules. . 2012. ISBN 978-1-4419-0460-7 - Vega-Moreno, Francisco Manuel:
VRK1:vaccinia-related kinase 1. Pag. 1992 - 1996. En: Encyclopedia of Signalling Molecules. . 2012. ISBN 978-1-4419-0460-7
Publicaciones en Revistas: - Colmenero-Repiso, Ana, Gómez, María De Los Ángeles, RODRIGUEZ-PRIETO, ISMAEL, Rivas-Infante, Eloy, Pardal-Redondo, Ricardo, Francisco M Vega:
Identification of VRK1 as a New Neuroblastoma Tumor Progression Marker Regulating Cell Proliferation. En: Cancers. 2020. Vol. 12. Núm. 11. Pag. 3465- - Huertas, Carlos, Gómez, María De Los Ángeles, Pardal-Redondo, Ricardo, Francisco M Vega:
Hypoxia in the Initiation and Progression of Neuroblastoma Tumours. En: International Journal of Molecular Sciences. 2019. Vol. 21. Núm. 1. Pag. 39-53 - Vega-Moreno, Francisco Manuel, Bolivar-Perez, Jorge, Pardal-Redondo, Ricardo, Garcia-Cozar, Francisco Jose, Aguado-Vidal, Enrique, Heck, Albert J.r. , Duran-Ruiz, Mª Carmen, Gautier, Violette, Fernandez-Ponce, Cecilia, Extremera, Maria Jesus, Altelaar, A.f.m., Millan, Jaime, Tellez, Juan C., Hernandez-campos, Jose A, Conejero, Rosario:
The atheroma plaque secretome stimulates the mobilization of endothelial progenitor cells ex vivo. En: Journal of Molecular and Cellular Cardiology. 2017. Vol. 105. Núm. . Pag. 12-23 10.1016/j.yjmcc.2017.02.001 - Linares-Clemente, Pedro, Mora, Jaume, Cabello-Laureano, Rosa María, Marquez-Vega, Catalina, Rivas-Infante, Eloy, Pardal-Redondo, Ricardo, Aguilar -Morante, Diana, RODRIGUEZ-PRIETO, ISMAEL, Ramirez-Villar, Gema Lucia, De Torres, Carolina, Santamaria, Vicente, Pascual-vaca, Diego, Colmenero-Repiso, Ana, Francisco M Vega:
Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in high-risk neuroblastoma . En: Oncotarget. 2017. Vol. 8. Núm. 52. Pag. 89775-89792 10.18632/oncotarget.21128 - Francisco M Vega, Ridley, Anne J.:
The RhoB small GTPase in physiology and disease. En: Small GTPases. 2016. Vol. Nov 2. Núm. . Pag. 1-10 10.1080/21541248.2016.1253528 - Moura, David S., Fernandez, Isabel F., Marín-royo, Gema, López-sánchez, Inmaculada, Martín-doncel, Elena, Francisco M Vega, Lazo-zbikowsqui, Pedro A.:
Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation. En: Scientific Reports. 2016. Vol. 6. Núm. . Pag. 28532- 10.1038/srep28532 - Erdreich-epstein, Anat, Campan, Mihaela, Morales, Guillermo, Garlich, Joseph R., Laird, Peter W. , Seeger, Robert C. , Shimada, Hiroyuki , Durden, Donald L., Singh, Alok R., Joshi, Shweta , Francisco M Vega, Guo, Pinzheng, Xu, Jingying, Groshen, Susan, Ye, Wei, Millard, Melissa:
Association of high microvessel ¿vß3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibi. En: Oncotarget. 2016. Vol. Nov 16. Núm. . Pag. - 10.18632/oncotarget.13386 - Francisco M Vega, Reymond, Nicolas, Thomas, Marian, Ridley, Anne J.:
The Rho GTPase RhoB regulates cadherin expression and epithelial cell-cell interaction . En: Cell Communication and Signaling [electronic resource]. 2015. Vol. 13. Núm. 6. Pag. - - Mártinez-criado, Yolanda, Cabella, Rosa, Fernández-pineda, Israel, Vega, F.M.:
Study of the expression of neural stem cell markers in neuroblastoma tumor samples and correlation with prognostic factors. En: Cirugía Pediátrica. 2013. Vol. 3. Núm. . Pag. 112-118 - Vega-Moreno, Francisco Manuel, Colomba, Audrey, Reymond, Nicolas, Thomas, Mairian, Ridley, Anne J.:
RhoB regulates cell migration through altered focal adhesion dynamics. En: Open Biology. 2012. Vol. 2. Núm. 5. Pag. 120076- 10.1186/s12964-015-0085-y - Reymond, Nicolas, Ridley, Anne J., Vega-Moreno, Francisco Manuel:
Cdc42 promotes transendothelial migration of cancer cells through BETA1 integrin. En: Journal of Cell Biology. 2012. Vol. 199. Núm. 4. Pag. 653-668 - Vega-Moreno, Francisco Manuel, Fruhwirth, G., Ng, Tony, Ridley, Anne J.:
RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. En: Journal of Cell Biology. 2011. Vol. 193. Núm. 4. Pag. 655-665 - Valbuena, Alberto, Sanz-garcía, Marta, López-sánchez, I., Vega-Moreno, Francisco Manuel, Lazo, Pedro A.:
Roles of VRK1 as a new player in the control of biological processes required for cell division. En: Cellular Signalling. 2010. Vol. 23. Núm. 8. Pag. 1267-1272 - Valbuena, Alberto, Blanco, Sandra, Vega-Moreno, Francisco Manuel, Lazo, Pedro A.:
The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53. En: PLoS One. 2008. Vol. 3. Núm. 7. Pag. 2649- - Vega-Moreno, Francisco Manuel, Ridley, Anne J.:
Rho GTPases in cancer cell biology. En: FEBS Letters. 2008. Vol. 582. Núm. 14. Pag. 2093-2101 - Durán, María Del Carmen, Vega-Moreno, Francisco Manuel, Moreno-bueno, G., Artiga, M.j., Sánchez, L., Palacios-Calvo, José, Ridley, Anne J., Timms, J.f.:
Characterisation of tumoral markers correlated with ErbB2 (HER2/Neu) overexpression and metastasis in breast cancer. En: Proteomics. Clinical Applications. 2008. Vol. 2. Núm. . Pag. 1313-1326 - Valbuena, Alberto, Lopez-sanchez, I., Vega-Moreno, Francisco Manuel, Sevilla, Ana, Sanz-garcía, Marta, Blanco, Sandra, Lazo, Pedro A.:
Identification of a human epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations. En: Archives of Biochemistry and Biophysics. 2007. Vol. 465. Núm. 1. Pag. 219-226 - Vega-Moreno, Francisco Manuel, Ridley, Anne J.:
Snapshot: Rho family GTPases. En: Cell. 2007. Vol. 129. Núm. 7. Pag. 1430-1431 - Santos, Claudio R., De Alava, Enrique, Sanchez-cespedes, M., Lazo, Pedro A., Rodriguez-pinilla, M., Vega-Moreno, Francisco Manuel, Rodriguez-peralto, J.l., Blanco, Sandra, Sevilla, Ana, Valbuena, Alberto, Hernandez, T., Van Wijnen, A.j.:
VRK1 Signaling pathway in the context of the proliferation phenotype in Head and Neck squamous cell carcinoma. En: Molecular Cancer Research. 2006. Vol. 4. Núm. 3. Pag. 177-185 - Blanco, Sandra, Klimcakova, L., Vega-Moreno, Francisco Manuel, Lazo, Pedro A.:
Subcellular localization of vaccinia-related kinase 2 (VRK2) isoforms determines their different effects on p53 stability in tumour cell lines. En: The FEBS Journal. 2006. Vol. 273. Núm. 1. Pag. 2487-2504 - Wheeler, A.p., Wells, C., Smith, S.d., Vega-Moreno, Francisco Manuel, Herderson, R.b., Tybulewicz, V.l., Ridley, Anne J.:
Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. En: Journal of Cell Science. 2006. Vol. 19. Núm. 13. Pag. 2749-2757 - Valbuena, Alberto, Vega-Moreno, Francisco Manuel, Lazo, Pedro A.:
p53 downregulates its activating vaccinia-related kinase 1 (VRK1) forming a new autoregulatory loop. En: Molecular and Cellular Biology. 2006. Vol. 26. Núm. 13. Pag. 4782-4793 - Sevilla, Ana, Santos, Claudio R., Vega-Moreno, Francisco Manuel, Lazo, Pedro A.:
Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with J. En: Journal of Biological Chemistry. 2004. Vol. 279. Núm. 26. Pag. 27458-27465 - Vega-Moreno, Francisco Manuel, Sevilla, Ana, Lazo, Pedro A.:
p53 Stabilization and accumulation induced by human vaccinia-related kinase 1. En: Molecular and Cellular Biology. 2004. Vol. 24. Núm. 23. Pag. 10366-10380 - Santos, Claudio R., Vega-Moreno, Francisco Manuel, Blanco, Sandra, Barcia, Ramón, Lazo, Pedro A.:
The vaccinia virus B1R kinase induces p53 downregulation by and Mdm2-dependent mechanism. En: Virology. 2004. Vol. 328. Núm. 2. Pag. 254-265 - Sevilla, Ana, Santos, Claudio R., Barcia, Ramón, Vega-Moreno, Francisco Manuel, Lazo, Pedro A.:
c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK). En: Oncogene. 2004. Vol. 23. Núm. 55. Pag. 8950-8958 - Vega-Moreno, Francisco Manuel, Gonzalo, P., Gaspar, Maria Luisa, Lazo, Pedro A.:
Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development. En: FEBS Letters. 2003. Vol. 544. Núm. . Pag. 176-180 - Barcia, Ramón, Lopez-borges, Susana, Vega-Moreno, Francisco Manuel, Lazo, Pedro A.:
Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1. En: Archives of Biochemistry and Biophysics. 2002. Vol. 399. Núm. . Pag. 1-5 - Martín-Rubio, María Esther, Hidalgo-Jimenez, Josefina, Vega-Moreno, Francisco Manuel, Velasco-Lopez, Angel:
Trimeric G proteins modulate the dynamic interaction of PKAII with the Golgi complex. En: Journal of Cell Science. 1999. Vol. 112. Núm. 22. Pag. 3869-3878
Aportaciones a Congresos: - Vega-Moreno, Francisco Manuel, Ridley, Anne J.:
Rho subfamily GTPases have distinct roles in migration and invasion by acting through different targets. Poster en Congreso. Frontiers in Cell Migration. BETHESDA, EE.UU. 2011 - Vega-Moreno, Francisco Manuel:
Rho subfamily GTPases have distinct roles in migration and invasion by acting through different targets. Conferencia Congreso no publicada. Actin 2010 UK Meeting. BRISTOL , REINO UNIDO. 2010 - Vega-Moreno, Francisco Manuel, Ridley, Anne J.:
Rho GTPases isoforms specificity in tumor cell migration and invasion. Poster en Congreso. Beatson International Cancer Conference: Microenviroment, Motility and Metastasis. GLASGOW - REINO UNIDO. 2009 - Vega-Moreno, Francisco Manuel, Ridley, Anne J.:
Investigating the roles of Rho isoforms in tumor cell invasion and migration . Poster en Congreso. Keystone Symposia: Cell Migration in Invasion and Inflammation. TAOS, NEW MEXICO (EEUU). 2008 - Vega-Moreno, Francisco Manuel:
Rho GTPases isoforms specificity in tumor cell migration and invasion. Conferencia Congreso no publicada. III Meeting in Cell Proliferation and Cancer. MALLORCA, ESPAÑA. 2008 - Vega-Moreno, Francisco Manuel, Ridley, Anne J.:
Gene silencing technology for the study of Rho GTPases in tumor cell invasion and migration. Poster en Congreso. Gordon Research Conference: Mechanisms of Cell Signalling. . 2007 - Vega-Moreno, Francisco Manuel, Ridley, Anne J.:
Gene silencing technology for the study of Rho GTPases in tumor cell invasion. Poster en Congreso. EMBO Worshop in Cell Migration, Tissue Invasion and Disease. CAPRI (ITALIA). 2006 - Vega-Moreno, Francisco Manuel:
Gene silencing technology for the study of Rho GTPases in tumor cell invasion. Conferencia Congreso no publicada. Actin 2006 UK meeting. BRISTOL , REINO UNIDO. 2006 - Vega-Moreno, Francisco Manuel:
The human kinase VRK1 and its role in the regulation of p53 tumor suppressor. Conferencia Congreso no publicada. XXVIII Congreso de la Sociedad española de Bioquimica y Biología Molecular (SEBBM). . 2005 - Vega-Moreno, Francisco Manuel, Lazo, Pedro A.:
p53 phosphorylation by the human vaccinia-related kinase 1 (VRK1). Poster en Congreso. International p53 workshop. . 2002
Tesis dirigidas y co-dirigidas: - Colmenero-Repiso, Ana:
Papel de la quinasa humana VRK1 en la biología del neuroblastoma. Tesis Doctoral. 2020
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