COMAILLS , Valentine Rosine Francoise

Perfil en ORCID: 0000-0001-8857-6976

Perfil en Scopus: 36476882200\

Responsable de los siguientes proyectos/ayudas en la US

Participa los siguientes proyectos/ayudas en la US

Proyectos:

• Genetic instability associated with epithelial to mesenchymal transition in cancer ( KG09042 - Investigador/a).

Contratos:

• Research specialist ( - Investigador/a ).
• Graduate researcher/ Ph.D student ( - Investigador/a ).
• Undergraduate research activity ( - Investigador/a ).
• Postdoctoral researcher ( - Investigador/a ).

Publicaciones

Publicaciones en Revistas:

• Comaills-, Valentine, Castellano-Pozo, Maikel:
  Chromosomal Instability in Genome Evolution: From Cancer to Macroevolution. En: Biology. 2023. Vol. . Núm. . Pag. - 10.3390/biology12050671
• Lorenzo, Petra I., Pérez-Cabello, Jesús Á., Rivero-Canalejo, Sabrina, Campos-Caro, Antonio, Claude-lachaud, Christian, Crespo-barreda, Alejandra, Aguilar-Diosdado, Manuel, García-fuentes, Eduardo , Martin-montalvo, Alejandro, Alvarez-Dolado, Manuel, Martin, Franz , Martín-vázquez, Eugenia, Rojo-Martínez, Gemma, Pozo-Pérez, David, Bermúdez-Silva, Francisco Javier, Comaills-, Valentine, Reyes, José C, Gauthier-, Benoit Raymond, López-Noriega, Livia, Fuente-martín, Esther, Mellado-Gil, Jose Manuel, Muñoz-Franco, Jaime, Cobo-Vuilleumier, Nadia, Guerrero-Martínez, Jose Antonio, Romero-Zerbo, Silvana Yanina:
  The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity . En: Theranostics. 2021. Vol. 11. Núm. 14. Pag. 6983-7004 10.7150/thno.57237
• Guo, Hongshan, Ebright , Richard Y , Horwitz, Elad , Vuille , Joanna A , Hajizadeh, Soroush , Wiley, Devon F , Reeves , Brittany A , Zhang, Jia-min , Niederhoffer, Kira L , Lu, Chenyue, Wesley , Benjamin , Golczer, Gabriel, Ho , Uyen, Nieman, Linda T, Toner , Mehmet , Vasudevan , Shobha , Zou, Lee , Mostoslavsky , Raul , Maheswaran , Shyamala , Lawrence , Michael S, Haber , Daniel A , Wittner, Ben S , Langenbucher, Adam , Zachariah , Marcus , Dubash, Taronish D , Hong, Xin , Comaills-, Valentine, Burr, Risa:
  NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer. En: Molecular Cell. 2021. Vol. 87. Núm. 19. Pag. 4041-4058 10.1016/j.molcel.2021.09.016
• Gauthier-, Benoit Raymond, Comaills-, Valentine:
  Nuclear envelope integrity in health and disease: Consequences on genome instability and inflammation. En: International Journal of Molecular Sciences. 2021. Vol. . Núm. . Pag. - 10.3390/ijms22147281
• Aceto, Nicola, Nielderhoffer, Kira, Zhu, Huili, Mackenzie, Olivia, Shioda, Toshi, Sgroi, Dennis, Kapur, Ravi, Ting, David T, Moy, Beverly, Ramaswamy, Sridhar, Toner, Mehmet, Bardia, Aditya, Haber, Daniel A, Maheswaran, Shyamala, Wittner, Ben S, Donaldson, Maria C, O'keefe, Ryan, Amgstron, Amanda, Bersani, Francesca, Zheng, Yu, Comaills-, Valentine:
  AR Expression in Breast Cancer CTCs Associates with Bone Metastases. En: Molecular Cancer Research. 2018. Vol. Apr;16. Núm. 4. Pag. 720-727 10.1158/1541-7786.MCR-17-0480
• Zheng, Yu, Broderick, Katherine T, Tai, Erik, Rengarajan, Shruthi, Kulkarni, Anupriya, Shioda, Toshi, Wu, Chin-lee, Ramaswamy, Sridhar, Ting, David T, Toner, Mehmet, Rivera, Miguel, Comaills-, Valentine, Maheswaran, Shyamala, Haber, Daniel A, Burr, Risa, Boulay, Gaylor, Miyamoto, David T, Wittner, Ben S, Emmons, Erin, Sil, Srinjoy, Koulopoulos, Michael W:
  COX-2 mediates tumor-stromal interaction through NR4A-induced Prolactin to initiate cancer proliferation. En: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2018. Vol. . Núm. . Pag. - paper accepted
• Domenici, Giacomo, Howard, Beatice, Kypta, Robert, Vivanco, Maria Del Mar, Aurrekoetexa-rodríguez, Iskander , Simoes, Bruno, Rabano, Miriam, So Young, Lee, San Millan, Julia, Comaills-, Valentine, Oliemuller, Erik, Lopez-Ruiz, Jose:
  A Sox2-Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells. En: Oncogene. 2018. Vol. . Núm. . Pag. - in press
• Zheng, Yu, Morris, Robert, Desai, Rushil, Desai, Niyati, Emmons, Erin, Milher, John D, Lee, Richard J, Wu, Chin-lee, Sequist, Lecia V, Haas, Wilhem, Ting, David T, Miyamoto, David T, Toner, Mehmet, Ramaswamy, Sridhar, Maheswaran, Shyamala, Haber, Daniel A, Wittner, Ben S, Sullivan, James P, Aceto, Nicola, Vincent-jordan, Nicole, Yu, Min, Karabacak, Nezihi Murat, Comaills-, Valentine:
  Expression of ß-globin by cancer cells promotes cell survival during blood-borne dissemination. En: Nature Communications. 2017. Vol. 8. Núm. 14344. Pag. - 10.1038/ncomms14344
• Yazinski, Stephanie A, Nussenzweig, Andre, Ramaswamy, Sridhar, Benes, Cyril H, Haber, Daniel A, Maheswaran, Shyamala, Birrer, Michael J, Zou, Lee, Comaills-, Valentine, Buisson, Remi, Genois, Marie-michelle, Nguyen, Hai Dang, Ho, Chu Kwen, Todorova-kwan, Tanya, Morris, Robert, Lauffer, Sam:
  ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells. En: Genes & Development. 2017. Vol. 31. Núm. 3. Pag. 318-332 www.genesdev.org/cgi/doi/10.1101/gad.290957.116.
• Cañete-Sánchez, Ana, Sanchez-Sanz, Maria Jose, Comaills-, Valentine, Prados-, Isabel Maria, Castro, Ana Maria, Hammad, Seddik , Ybot-Gonzalez, Patricia, Bockamp, Ernesto , Hengstler, Jan G , Gottgens, Bertie:
  Characterization of a Fetal Liver Cell Population Endowed with Long-Term Multiorgan Endothelial Reconstitution Potential. En: Stem Cells. 2017. Vol. 35. Núm. 2. Pag. 507-521 10.1002/stem.2494
• Comaills-, Valentine, Pan, Shiwei, Aceto, Nicola, Sil, Srinjoy, Zheng, Yu , Sundaresan, Tilak, Yae, Toshifumi, Vincent Jordan, Nicole, Miyamoto, David T, Ting, David T, Ramaswamy, Sridhar, Kabeche, Lilian, Haas, Wilhem, Zou, Lee, Haber, Daniel A, Maheswaran, Shyamala, Morris, Robert, Buisson, Remi, Yu, Min, Wells Malden, Marissa, Licausi, Joseph, Boukhali, Myriam, Tajima, Ken:
  Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition. En: Cell Reports. 2016. Vol. 17. Núm. 10. Pag. 2632-2647 https://doi.org/10.1016/j.celrep.2016.11.022
• Tajima, Ken, Takahashi, Fumiyuki, Black, Joshua C, Ramaswamy, Sridhar , Shioda, Toshihiro, Hammell, Molly, Haber, Daniel A, Whetsine, Johnathan R, Maheswaran, Shyamala, Yae, Toshifumi, Javaid, Sarah, Tam, Oliver, Comaills-, Valentine, Morris, Robert , Wittner, Ben S, Liu, Mingzhu, Engstrom, Amanda:
  SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes. En: Nature Communications. 2015. Vol. 6. Núm. 8257. Pag. - doi: 10.1038/ncomms9257
• Piva, Marco, Kypta, Robert, Vivanco, Maria Del Mar, Domenici , Giacomo, Iriondo, Oihana, Rabano, Miriam, Simoes, Bruno, Comaills-, Valentine, Barredo, Ignacio, Lopez-ruiz, Ja, Zabalza, I:
  Sox2 promotes tamoxifen resistance in breast cancer cells. En: EMBO Molecular Medicine. 2014. Vol. Jan;6. Núm. 1. Pag. 66-79 10.1002/emmm.201303411
• Yu, Min, Zheng, Zongli, Wittner, Ben S, Stojanov, Petar, Brachtel, Elena, Sgroi, Dennis, Kapur, Ravi, Shioda, Toshihiro, Ting, David T, Ramaswamy, Sridhar, Getz, Gad, Bardia, Aditya, Iafrate, A. John, Benes, Cyril, Maheswaran, Shyamala, Haber, Daniel A, Aceto, Niocola, Bersani, Francesca, Madden, Marissa W, Donalson, Maria C, Desai, Rushil, Zhu, Huili, Comaills-, Valentine:
  Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility. En: Science. 2014. Vol. 345 . Núm. 6193. Pag. 216-220 10.1126/science.1253533
• Chiba, Naokazu, Brachtel, Elena, Vivanco, Maria Del Mar, Haber, Daniel A, Zou, Lee, Maheswaran, Shyamala, Comaills-, Valentine, Shiotani, Bunsyo, Takahashi, Funiyuki, Shimada, Toshiyuki, Tajima, Ken , Winokur, Daniel, Hayashida, Tetsu, Willers, Henning:
  Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses. En: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2012. Vol. 109. Núm. 8. Pag. 2760-2765 https://doi.org/10.1073/pnas.1018867108
• Simoes, Bruno, Piva, Marco, Iriondo, Oihana, Comaills-, Valentine, Lopez-ruiz, Jose A, Zabalza, Inaki, Mieza, Jon A, Acinas, Olga, Vivanco, Maria Del Mar:
  Effects of estrogen on the proportion of stem cells in the breast. En: Breast Cancer Research and Treatment. 2011. Vol. 129. Núm. 1. Pag. 23-35 10.1007/s10549-010-1169-4

Aportaciones a Congresos:

• Comaills-, Valentine:
  Proliferation during epithelial to mesenchymal transition induces genomic instability. Poster en Congreso. AACR Annual Meeting 2017. WASHINGTON, ESTADOS UNIDOS. 2017
• Comaills-, Valentine:
  EMT induced genetic instability. Ponencia en Congreso. TEMTIA VIII / International EMT meeting. houston EEUU. 2017
• Comaills-, Valentine:
  Induction of ß-globin protects circulating tumor cells from oxidative stress during dissemination. Poster en Congreso. AACR Annual Meeting 2016. NEW ORLEANS, EE UU. 2016