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d'Anglemont de Tassigny , XavierPerfil en ORCID: 0000-0002-5346-1156 Perfil en ResearcherID: C-3916-2015 Perfil en Scopus: 24830354600\ Grupos de Investigación - FISIOLOGIA CELULAR Y BIOFISICA
Responsable de los siguientes proyectos/ayudas en la USParticipa los siguientes proyectos/ayudas en la USProyectos: - Red de Terapia Celular (TerCel) ( RD16/0011/0025 - Investigador/a).
- "Molecular mechanisms of acute oxygen sensing (OXYGENSENSING)" ( 2629/0805 - Investigador/a).
- Molecular mechanism of acute oxygen sensing ( PRJ201502629 - Participante).
- Efectos de la hipoxia crónica sobre la neurogénesis en el adulto: protección y rescate del nicho neurogénico ( CP12/03217 - Investigador Principal Joven).
- Sensibilidad al Oxígeno y Neurodegeneración ( SAF2012-39343 - Investigador/a).
Ayudas: - Neuroprotection in Parkinson's disease; a potential therapy based on stimulation of endogenous GDNF production ( XDTBBVA2015 - Investigador Principal Joven ).
PublicacionesPublicaciones en Revistas: - Enterría-Morales, Daniel, Lopez-Lopez, Ivette, Lopez-Barneo, Jose, D'anglemont De Tassigny, Xavier:
Molecular targets for endogenous glial cell line-derived neurotrophic factor modulation in striatal parvalbumin interneurons. En: Brain Communications. 2020. Vol. 2. Núm. 2. Pag. - 10.1093/braincomms/fcaa105 - Enterría-Morales, Daniel, Lopez-Lopez, Ivette, Lopez-Barneo, Jose, D'anglemont De Tassigny, Xavier:
Role of glial cell line-derived neurotrophic factor in the maintenance of adult mesencephalic catecholaminergic neurons. En: Movement disorders. 2020. Vol. . Núm. . Pag. - 10.1002/mds.27986 - Dong, C, Helton, Es, Zhou, P, Ouyang, X, D'anglemont De Tassigny, Xavier, Pascual, Alberto, Lopez-Barneo, Jose, Ubogu, Ee:
Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neu. En: Tissue Barriers. 2018. Vol. 6. Núm. 2. Pag. 1-22 10.1080/21688370.2018.1479570 - D'anglemont De Tassigny, Xavier, Jayasena, Channa, Murphy, Kevin G, Dhillo, Waljit S, Colledge, William H:
Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo. En: PLoS One. 2017. Vol. . Núm. e0176821. Pag. - 10.1371/journal.pone.0176821 - D'anglemont De Tassigny, Xavier:
Outlook on the neuroprotective effect of estrogen.. En: Neural Regeneration Research. 2017. Vol. 12. Núm. 11. Pag. 1799-1800 10.4103/1673-5374.219036 - Enterría-Morales, Daniel, Lopez-Lopez, Ivette, Lopez-Barneo, Jose, D'anglemont De Tassigny, Xavier:
Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan-Neuronal Activation in the Female Mouse.. En: PLoS One. 2016. Vol. 11. Núm. 10. Pag. e0164391- 10.1371/journal.pone.0164391 - D'anglemont De Tassigny, Xavier, Pascual, Alberto, Lopez-Barneo, Jose:
GDNF-based therapies, GDNF-producing interneurons, and trophic support of the dopaminergic nigrostriatal pathway. Implications for Parkinson's disease. En: Frontiers in Neuroanatomy. 2015. Vol. 9. Núm. 10. Pag. - 10.3389/fnana.2015.00010. eCollection 2015 - D'anglemont De Tassigny, Xavier, Pardal-Redondo, Ricardo, Lopez-Lopez, Ivette, Lopez-Barneo, Jose:
Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuron. En: Hypoxia. 2015. Vol. . Núm. 3. Pag. 15-33 10.2147/HP.S78248 - Bellefontaine, Charlotte, Chachlaki, Konstantina, Parkhash, Jyoti, Vanacker, Charlotte, Colledge, William H., D'anglemont De Tassigny, Xavier, Garthwaite, John, Bouret, Sebastien G., Prevot, Vincent:
Leptin-dependent neuronal NO signaling in the preoptic hypothalamus facilitates reproduction.. En: Journal of Clinical Investigation. 2014. Vol. 128. Núm. 6. Pag. 2550-2559 10.1172/JCI65928 - D'anglemont De Tassigny, Xavier:
Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation.. En: The Journal of Neuroscience. 2012. Vol. 32. Núm. 3. Pag. 932-945 10.1523/JNEUROSCI.4765-11.2012 - D'anglemont De Tassigny, Xavier:
Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus.. En: The Journal of Comparative Neurology. 2011. Vol. 519. Núm. 17. Pag. 3456-3469 10.1002/cne.22716 - D'anglemont De Tassigny, Xavier:
The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent. En: BMC Genomics. 2011. Vol. . Núm. . Pag. - 10.1186/1471-2164-12-209 - D'anglemont De Tassigny, Xavier:
Inotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptor. En: PLoS One. 2011. Vol. 6. Núm. 11. Pag. - 10.1371/journal.pone.0027601 - D'anglemont De Tassigny, Xavier:
Nitric oxide as key mediator of neuron-to-neuron and endothelia-to-glia communication involved in the neuroendocrine control of reproduction.. En: Neuroendocrinology. 2011. Vol. 93. Núm. 2. Pag. 74-89 10.1159/000324147 - D'anglemont De Tassigny, Xavier:
Mll5 is required for normal spermatogenesis.. En: PLoS One. 2011. Vol. 6. Núm. 11. Pag. - 10.1371/journal.pone.0027127 - D'anglemont De Tassigny, Xavier:
Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excit. En: The Journal of Neuroscience. 2011. Vol. 31. Núm. 7. Pag. 2421-2430 10.1523/JNEUROSCI.5759-10.2011 - D'anglemont De Tassigny, Xavier:
Role of estradiol in the dynamic control of tanycyte plasticity mediated by vascular endothelial cells in the median eminence.. En: Endocrinology. 2010. Vol. 151. Núm. 4. Pag. 1760-1772 10.1210/en.2009-0870 - D'anglemont De Tassigny, Xavier:
Mouse models to study the central regulation of puberty.. En: Molecular and Cellular Endocrinology. 2010. Vol. 324. Núm. 1-2. Pag. 12-20 10.1016/j.mce.2010.01.015 - D'anglemont De Tassigny, Xavier:
Distribution and postnatal development of Gpr54 gene expression in mouse brain and gonadotropin-releasing hormone neurons.. En: Endocrinology. 2010. Vol. 151. Núm. 1. Pag. 312-321 doi: 10.1210/en.2009-0552 - D'anglemont De Tassigny, Xavier:
Function-related structural plasticity of the GnRH system: a role for neuronal-glial-endothelial interactions.. En: Frontiers in Neuroendocrinology. 2010. Vol. 31. Núm. 3. Pag. 241-258 10.1016/j.yfrne.2010.05.003 - D'anglemont De Tassigny, Xavier:
Kisspeptin signaling is required for peripheral but not central stimulation of gonadotropin-releasing hormone neurons by NMDA.. En: The Journal of Neuroscience. 2010. Vol. 30. Núm. 25. Pag. 8581-8590 10.1523/JNEUROSCI.5486-09.2010 - D'anglemont De Tassigny, Xavier:
Phosphorylation of N-methyl-D-aspartic acid receptor-associated neuronal nitric oxide synthase depends on estrogens and modulates hypothalamic nitric . En: Endocrinology. 2010. Vol. 151. Núm. 6. Pag. 2723-2735 10.1210/en.2010-0007 - D'anglemont De Tassigny, Xavier:
The role of kisspeptin signaling in reproduction.. En: Physiology. 2010. Vol. 25. Núm. 4. Pag. 207-217 10.1152/physiol.00009.2010 - D'anglemont De Tassigny, Xavier:
Distribution of kisspeptin neurones in the adult female mouse brain.. En: Journal of Neuroendocrinology. 2009. Vol. 21. Núm. 8. Pag. 673-682 10.1111/j.1365-2826.2009.01892.x - D'anglemont De Tassigny, Xavier:
Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor . En: Journal of Neurochemistry. 2009. Vol. 109. Núm. 1. Pag. 214-224 10.1111/j.1471-4159.2009.05949.x - D'anglemont De Tassigny, Xavier:
The role of kisspeptin signalling in the regulation of the GnRH-gonadotrophin ovarian axis in mice.. En: Annales d'Endocrinologie. 2008. Vol. 71. Núm. 3. Pag. 198-200 10.1016/j.ando.2010.02.011 - D'anglemont De Tassigny, Xavier:
Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge.. En: The Journal of Neuroscience. 2008. Vol. 28. Núm. 35. Pag. 8691-8697 10.1523/JNEUROSCI.1775-08.2008 - D'anglemont De Tassigny, Xavier:
Coupling of neuronal nitric oxide synthase to NMDA receptors via postsynaptic density-95 depends on estrogen and contributes to the central control of. En: The Journal of Neuroscience. 2007. Vol. 27. Núm. 23. Pag. 6103-6114 - D'anglemont De Tassigny, Xavier:
Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.. En: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2007. Vol. 104. Núm. 25. Pag. 10714-10719
Aportaciones a Congresos: - D'anglemont De Tassigny, Xavier:
Pharmacological stimulation of endogenous GDNF in the striatum: towards a future neuroprotective therapy in Parkinson¿s disease?. Sesión no plenaria en Congreso. VI International Congress on Research and Innovation in Neurodegenerative Diseases. XII CIBERNED Scientific Forum.. - Santiago de Compostela (A Coruña), España. 2018 - D'anglemont De Tassigny, Xavier:
Towards a specific stimulation of endogenous GDNF production by striatal parvalbumin interneurons. Comunicación en congreso. International Conference on Neurotrophic Factors 2018. - Salamanca, España. 2018 - D'anglemont De Tassigny, Xavier, Enterría-Morales, Daniel, Lopez-Lopez, Ivette, Lopez-Barneo, Jose:
Stimulation of endogenous striatal GDNF: a neuroprotective therapy for Parkinson¿s disease?. Poster en Congreso. NeuroFrance. BURDEOS (FRANCIA). 2017 - Enterría-Morales, Daniel, Lopez-Lopez, Ivette, Lopez-Barneo, Jose, D'anglemont De Tassigny, Xavier:
Molecular insights into the endogenous GDNF expression of striatal parvalbumin neurons: a possible tool for neuroprotective therapy for Parkinson¿s di. Poster en Congreso. SfN Annual Meeting. WASHINGTON DC (EEUU). 2017 - D'anglemont De Tassigny, Xavier, Enterría-Morales, Daniel, Lopez-Lopez, Ivette, Lopez-Barneo, Jose:
Transcriptomic changes in parvalbumin positive interneurons expressing Cre recombinase. Poster en Congreso. SfN Annual Meeting. WASHINGTON DC (EEUU). 2017
Patentes: - Lopez-Barneo, Jose, D'anglemont De Tassigny, Xavier, Enterría-Morales, Daniel, Lopez-Lopez, Ivette:
Composiciones capaces de modular la estimulación de GDNF endógeno para el tratamiento de enfermedades neurodegenerativas. Otra modalidad de propiedad industrial. Solicitud: 29/08/2017
Tesis dirigidas y co-dirigidas: - :
Estimulación del GDNF endógeno en el estriado de ratón.. Tesis Doctoral. 2019
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